Abstract Background The Ehlers-Danlos syndromes (EDS) are rare connective tissue disorders consisting of 13 subtypes with overlapping features including joint hypermobility. skin and generalized connective tissue fragility. Classical EDS (cEDS) is principally caused by heterozygous COL5A1 or COL5A2 variants and rarely by the COL1A1 p. (Arg312Cys) substitution. https://parisnaturalfoodes.shop/product-category/org-sprouted-whole-grain-tortillas/