In order to preserve structure and function. proteins tend to preferentially conserve amino acids at particular sites along the sequence. Because mutations can affect structure and function. the question arises whether the preference of a protein site for a particular amino acid varies between protein homologs. https://parisnaturalfoodes.shop/product-category/tart-cherry-concentrate/
Gene Families, Epistasis and the Amino Acid Preferences of Protein Homologs
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