The insulin receptor (IR) presents by alternative splicing two isoforms: IRA and IRB. The differential physiological and pathological role of both isoforms is not completely known. and it is determinant the different binding affinity for insulin-like growth factor. IRB is more abundant in adult tissues and it exerts mainly the metabolic actions of insulin. https://www.bekindtopets.com/top-price-Disney-Bambi-Thumper-Character-Pattern-Galaxy-S23-Clear-Case-p110724-huge-savings/