BACKGROUND: Creatine Kinases (CK) catalyze the reversible transfer of high-energy phosphate groups between ATP and phosphocreatine. thereby playing a storage and distribution role in cellular energetics. Brain-type CK (CK-B) deficiency is coupled to loss of function in neural cell circuits. altered bone-remodeling by osteoclasts and complement-mediated phagocytotic activity of macroph... https://www.roneverhart.com/Nef-Rune/